发明名称 |
RECOMBINANT PROBIOTIC BACTERIA FOR THE PREVENTION AND TREATMENT OF INFLAMMATORY BOWEL DISEASE (IBD) AND IRRITABLE BOWEL SYNDROME (IBS) |
摘要 |
The present invention relates to the general field of therapy of Inflammatory Bowel Disease (IBD) and/or Irritable Bowel Syndrome (IBS). Thus, the invention relates to a molecule selected from the trappin-2 protein or an active fraction thereof, a member of the WAP family proteins or an active fraction thereof or a member of the Serpin family proteins or an active fraction thereof for the treatment of Irritable Bowel Syndrome (IBS). The invention also relates to a recombinant food-grade bacterium comprising a gene selected from a gene coding for the trappin-2 protein or an active fraction thereof, a gene coding for a member of the WAP family proteins or an active fraction thereof, or a gene coding for a member of the Serpin family proteins or an active fraction thereof. |
申请公布号 |
US2012195859(A1) |
申请公布日期 |
2012.08.02 |
申请号 |
US201213357063 |
申请日期 |
2012.01.24 |
申请人 |
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发明人 |
VERGNOLLE NATHALIE;SALLENAVE JEAN-MICHEL;LANGELLA PHILIPPE;BERMUDEZ-HUMARAN LUIS |
分类号 |
A61K35/74;A61P1/00;A61P11/00;A61P13/00;A61P15/00;A61P19/02;A61P29/00;C07K14/81;C12N1/21 |
主分类号 |
A61K35/74 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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