发明名称 |
METHOD AND COMPOSITION FOR PRODUCING ACTIVE VITAMIN K-DEPENDENT PROTEIN |
摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method and a composition for producing an active vitamin K-dependent protein. <P>SOLUTION: There is provided a method for increasing the quantity of a carboxylated vitamin K-dependent protein in a cell including a step to introduce a second heterologous nucleic acid encoding vitamin K epoxide reductase (VKOR) into a cell expressing a first nucleic acid encoding a vitamin K-dependent protein under a condition to express the first nucleic acid and the second nucleic acid and produce the vitamin K-dependent protein and VKOR. <P>COPYRIGHT: (C)2012,JPO&INPIT |
申请公布号 |
JP2012139232(A) |
申请公布日期 |
2012.07.26 |
申请号 |
JP20120058816 |
申请日期 |
2012.03.15 |
申请人 |
UNIV OF NORTH CAROLINA AT CHAPEL HILL |
发明人 |
STAFFORD DARREL W;LI TAO |
分类号 |
C12P21/02;C12N5/10;C12N15/09 |
主分类号 |
C12P21/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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