发明名称 |
Combination of Single-Cell Electroporation and Electrical Recording Using the Same Electrode |
摘要 |
Methods for stimulating exocytosis from a cell are provided where the same electrochemical microelectrode is used to electroporate an adjacent cell and then measure quantal exocytosis from the adjacent cell. Also provided are methods for stimulating and measuring exocytosis from a select cell population arrayed on a chip comprising addressable electrodes. Calcium independent stimulation of exocytosis with inorganic anions such as chloride ions is also provided. These methods can provide for specific stimulation of a desired subset of cells without exposing other nearby cells to the stimulus.
|
申请公布号 |
US2012190583(A1) |
申请公布日期 |
2012.07.26 |
申请号 |
US201213359408 |
申请日期 |
2012.01.26 |
申请人 |
GILLIS KEVIN;GHOSH JAYA;THE CURATORS OF THE UNIVERSITY OF MISSOURI |
发明人 |
GILLIS KEVIN;GHOSH JAYA |
分类号 |
C40B30/06;G01N27/00 |
主分类号 |
C40B30/06 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|