CHIMERIC PEPTIDES INCLUDING A PENETRATING PEPTIDE AND A BINDING DOMAIN OF PP2A CATALYTIC SUBUNIT TO CASPASE-9
摘要
The invention related to chimeric peptides including a penetrating peptide and a binding domain of PP2A catalytic subunit to caspase-9 which have pro-apoptotic activity. These chimeric peptides may be used for the treatment of hyperproliferative disorders.
申请公布号
WO2012042038(A3)
申请公布日期
2012.07.26
申请号
WO2011EP67173
申请日期
2011.09.30
申请人
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM);REBOLLO GARCIA, ANGELITA;DECAUDIN, DIDIER;NEMATI, FARIBA;INSTITUT CURIE