Inactivatable target capture oligomers for use in the selective hybridization and capture of target nucleic acid sequences

摘要

An inactivatable target capture oligomer comprising at least: (i) a binding pair member; (ii) a target hybridizing region that is at least 15 nucleobases in length; and (iii) a tag-closing region that is at least 3 nucleobases in length; wherein the tag-closing region nucleic acid sequence is substantially complementary to a portion of the target hybridizing region nucleic acid sequence, and wherein the binding pair member, the target hybridizing region and the tag-closing region are joined as a single molecule.