发明名称 Pharmaceutical process and intermediates 714
摘要 The invention relates to compounds of formula (X), and salts thereof, and their use as intermediates in improved manufacturing processes for the synthesis of pharmaceutical compound (I): X is ═O, ═N—OH or ═N—OC(O)Me; Y is hydrogen, PhS- or p-chlorophenylsulfanyl; Z is hydrogen or —CH2COOR1 wherein R1 is selected from hydrogen, optionally substituted hydrocarbyl and optionally substituted heterocyclyl.
申请公布号 US8227622(B2) 申请公布日期 2012.07.24
申请号 US20100830577 申请日期 2010.07.06
申请人 AINGE DEBRA;MERIFIELD ERIC;THOMSON COLIN;BUTTERS MICHAEL;RAMAKRISHNAN RAVI;RAYAPATI RAVI NAIDU;SHARMA PARHALAD RAY;ASTRAZENECA AB 发明人 AINGE DEBRA;MERIFIELD ERIC;THOMSON COLIN;BUTTERS MICHAEL;RAMAKRISHNAN RAVI;RAYAPATI RAVI NAIDU;SHARMA PARHALAD RAY
分类号 C07D209/30;C07D209/12 主分类号 C07D209/30
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