发明名称 Pharmaceutical compounds
摘要 Pyrazole derivatives of the following formula (I), having affinity for the cannabinoidergic CB1 and/or CB2 receptors: wherein: R is a group selected from C1-C10 alkyl; aryl, arylalkyl or arylalkenyl, not substituted or having from one to four substituents, equal to or different from each other; A is a group selected from the following: an ether group of formula —(CH2)—O—(CH2)v—R″ wherein v is equal to 1 or 2; R″ is as defined in the present application; a ketone group of formula —C(O)—Z′, wherein Z′ is as defined in the present application; a substituent having an hydroxyl function of formula —CH(OH)—Z′, being as defined in the present application; an amide substituent of formula —C(O)—NH-T′, T′ being as defined in the present application; B is a group as defined in the present application; D is an heteroaryl optionally substituted.
申请公布号 US8227620(B2) 申请公布日期 2012.07.24
申请号 US20090645415 申请日期 2009.12.22
申请人 LAZZARI PAOLO;RUIU STEFANIA;PINNA GERARD AIME;MURINEDDU GABRIELE;NEUROSCIENZE PHARMANESS S.C. A.R.L. 发明人 LAZZARI PAOLO;RUIU STEFANIA;PINNA GERARD AIME;MURINEDDU GABRIELE
分类号 A61K31/4155;A61K31/4453;A61K31/454;A61K31/55;A61K47/20;A61P1/08;A61P1/16;A61P3/00;A61P7/06;A61P9/00;A61P11/00;A61P13/00;A61P13/12;A61P17/00;A61P19/02;A61P19/08;A61P19/10;A61P21/00;A61P25/00;A61P25/06;A61P25/08;A61P25/14;A61P25/16;A61P25/18;A61P25/24;A61P25/28;A61P25/30;A61P27/02;A61P29/00;A61P37/00;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07D409/04 主分类号 A61K31/4155
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