| 摘要 |
A method, system and apparatus for processing requests is provided. The method comprises storing, in a memory, splicing code data comprising a plurality of features, the splicing code data further comprising, in association with each feature, at least one parameter defining the activity of the feature in splicing regulation; receiving a request at a processor, the request identifying at least a first portion of a genomic sequence; receiving, at the processor, at least a second portion of the genomic sequence that is relevant to the first portion; generating, at the processor, a feature set comprising at least one feature from the second portion of the genomic sequence; generating, based on the splicing code data and the feature set, a response to the request, the response comprising at least one of predicted changes in inclusion levels and a predicted feature map for at least one condition; and transmitting the response. |
