发明名称 |
DONEPEZIL TRANSDERMAL PATCH |
摘要 |
The present invention relates to a donepezil transdermal patch comprising a backing layer and a pressure sensitive adhesive matrix layer, wherein the pressure sensitive adhesive matrix layer comprises donepezil free base and an acrylic pressure sensitive adhesive agent selected from the group consisting of a copolymer of 2-ethylhexyl acrylate and vinyl acetate and a copolymer of 2-ethylhexyl acrylate, vinyl acetate, and hydroxyl-containing monomers, and wherein 2-ethylhexyl acrylate is present in an amount of about 65% to about 75%, vinyl acetate is present in an amount of about 25% to about 35%, and the hydroxyl-containing monomers are in an amount of about 0% to about 10%, based on the total weight of the copolymer. |
申请公布号 |
WO2012097197(A1) |
申请公布日期 |
2012.07.19 |
申请号 |
WO2012US21145 |
申请日期 |
2012.01.12 |
申请人 |
KO, SHAWN;TAIWAN BIOTECH CO., LTD;YANG, KUO-HUA;YANG, CHIH-SHENG;LIN, HSUEN-YAU |
发明人 |
YANG, KUO-HUA;YANG, CHIH-SHENG;LIN, HSUEN-YAU |
分类号 |
A61K9/70;A61K31/445;C07D211/06 |
主分类号 |
A61K9/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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