| 发明名称 |
A monoclonal antibody to CD44 for use in the treatment of head and neck squamous cell carcinoma |
| 摘要 |
<p>A monoclonal anti-CD44 antibody, or antigen-binding fragment thereof, for use in the treatment of a head and neck squamous cell carcinoma (HNSCC) in a mammal, wherein said HNSCC is characterized by the expression of CD44. Said monoclonal antibody may be produced by the hybridoma deposited with the ATCC with the accession number PTA-4621, and may be chimeric or humanized versions thereof.</p> |
| 申请公布号 |
AU2011212485(A1) |
申请公布日期 |
2012.07.19 |
| 申请号 |
AU20110212485 |
申请日期 |
2011.02.02 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG;UNIVERSITY OF MIAMI |
发明人 |
DA CRUZ, LUIS A.G.;FRANZMANN, ELIZABETH JANE |
| 分类号 |
C07K16/28;A61K39/395;A61P35/00 |
主分类号 |
C07K16/28 |
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