METHODS FOR SCREENING COMPOUNDS FOR CAPABILITY TO INHIBIT PREMALIGNANT SQUAMOUS EPITHELIAL CELL PROGRESSION TO A MALIGNANT STATE
摘要
Methods for screening compounds for their capability to inhibit CYP1B1-mediated proliferation and motility of and/or to reverse estrogen-induced reduction in apoptosis of premalignant or malignant cells are provided. Kits for practicing the screening methods are also provided.
申请公布号
WO2012058550(A3)
申请公布日期
2012.07.19
申请号
WO2011US58306
申请日期
2011.10.28
申请人
FOX CHASE CANCER CENTER;CLAPPER, MARGIE;SHATALOVA, EKATERINA