发明名称 COMPOSITIONS AND METHODS OF USE FOR THERAPEUTIC ANTIBODIES
摘要 The present invention relates to antibodies that specifically bind to the BAFF receptor (BAFFR). The invention more specifically relates to specific antibodies that are BAFFR antagonists with in vivo B cell depleting activity and compositions and methods of use for said antibodies to treat pathological disorders that can be treated by killing or depleting B cells, such as systemic lupus erythematosus or rheumatoid arthritis or other autoimmune diseases or lymphomas, leukemias and myelomas.
申请公布号 US2012183529(A1) 申请公布日期 2012.07.19
申请号 US201113326514 申请日期 2011.12.15
申请人 发明人 HEUSSER CHRISTOPH;NEUGEBAUER JULIA;SCHAADT EVELINE;URLINGER STEFANIE;WOISETSCHLAEGER MAXIMILIAN
分类号 A61K39/395;A61P19/02 主分类号 A61K39/395
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