发明名称 Macrocyclic oximyl hepatitis C serine protease inhibitors
摘要 The present invention relates to compounds of Formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising a compound of the present invention.
申请公布号 US8222203(B2) 申请公布日期 2012.07.17
申请号 US20080333457 申请日期 2008.12.12
申请人 SUN YING;GAI YONGHUA;OR YAT SUN;WANG ZHE;ENANTA PHARMACEUTICALS, INC. 发明人 SUN YING;GAI YONGHUA;OR YAT SUN;WANG ZHE
分类号 A61K38/00 主分类号 A61K38/00
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