| 摘要 |
The invention comprises a process for the production of 3,5-dinitro-o-toluic acid, by reacting 1 molar equivalent of o-toluic acid, with at least about 2 molar equivalents of nitric acid, and at least about 10 molar equivalents of sulphuric acid, the latter two acids being of such concentration that the water content of the reaction mixture does not exceed about 15% by weight, based on the total weight of the sulphuric and nitric acids in the reaction mixture, at 25-110 DEG C., until substantial reaction has occurred, adjusting the temperature to about 0-30 DEG C., and separating from the mixture the thus formed crystals of 3,5-dinitro-o-toluic acid. The reaction may be carried out in the presence of an inert solvent such as a chlorinated C1-C4 aliphatic hydrocarbon. The process may also be applied to other o-alkyl benzoic acids. Examples are given. |
