发明名称 |
INDOLE DERIVATIVE HAVING PIPERIDINE RING |
摘要 |
The present invention relates to a compound represented by the following formula, a pharmacologically acceptable salt thereof, or a use thereof as a pharmaceutical: [Formula 1] (see formula 1) wherein R1 and R2 are substituents adjacent to each other, and together with two carbon atoms to each of which they attach, form a 5- to 7-membered non-aromatic carbocyclic group or the like, which may be substituted by 1 to 4 substituents selected from (1) an oxo group, (2) a hydroxyl group, and the like; R3 represents a hydrogen atom or the like; and R6 represents a hydrogen atom or the like. This compound has a superior strength of binding to a 5-HT1A receptor and an antagonism to the receptor, and is useful as an agent for treating or preventing lower urinary tract symptoms, and particularly symptoms regarding urinary storage.
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申请公布号 |
CA2564062(C) |
申请公布日期 |
2012.07.10 |
申请号 |
CA20052564062 |
申请日期 |
2005.05.11 |
申请人 |
EISAI R & D MANAGEMENT CO., LTD. |
发明人 |
SUZUKI, YUICHI;ITO, KOICHI;SASAKI, ATSUSHI;UENO, KOSHI;SAKAI, MIYUKI;ISHIHARA, HIROKI;KUBOTA, ATSUHIKO |
分类号 |
C07D405/14;A61K31/454;A61K31/4725;A61K31/536;A61K31/55;A61K31/553;A61P13/02;A61P13/10;A61P43/00;C07D401/04;C07D401/14;C07D413/14;C07D417/14;C07D491/08 |
主分类号 |
C07D405/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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