发明名称 INDOLE DERIVATIVE HAVING PIPERIDINE RING
摘要 The present invention relates to a compound represented by the following formula, a pharmacologically acceptable salt thereof, or a use thereof as a pharmaceutical: [Formula 1] (see formula 1) wherein R1 and R2 are substituents adjacent to each other, and together with two carbon atoms to each of which they attach, form a 5- to 7-membered non-aromatic carbocyclic group or the like, which may be substituted by 1 to 4 substituents selected from (1) an oxo group, (2) a hydroxyl group, and the like; R3 represents a hydrogen atom or the like; and R6 represents a hydrogen atom or the like. This compound has a superior strength of binding to a 5-HT1A receptor and an antagonism to the receptor, and is useful as an agent for treating or preventing lower urinary tract symptoms, and particularly symptoms regarding urinary storage.
申请公布号 CA2564062(C) 申请公布日期 2012.07.10
申请号 CA20052564062 申请日期 2005.05.11
申请人 EISAI R & D MANAGEMENT CO., LTD. 发明人 SUZUKI, YUICHI;ITO, KOICHI;SASAKI, ATSUSHI;UENO, KOSHI;SAKAI, MIYUKI;ISHIHARA, HIROKI;KUBOTA, ATSUHIKO
分类号 C07D405/14;A61K31/454;A61K31/4725;A61K31/536;A61K31/55;A61K31/553;A61P13/02;A61P13/10;A61P43/00;C07D401/04;C07D401/14;C07D413/14;C07D417/14;C07D491/08 主分类号 C07D405/14
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