摘要 |
<P>PROBLEM TO BE SOLVED: To provide a vaccine, obtained by using an inactivated antigen for preventing salmonellosis causing lethal and systemic respiratory or digestive disease. <P>SOLUTION: Specified salt and organic acid are added to a medium culture for salmonella proliferation, to induce the expression of defense-associated protein having an effect of increasing immune response reaction. The obtained fungus body is inactivated, and is combined with adjuvant mainly composed of liposome. Thereby obtaining an inactivated vaccine for salmonella having high practicality. <P>COPYRIGHT: (C)2012,JPO&INPIT |