发明名称 |
PROFILING FRAGMENTS OF ELASTIC FIBERS AND MICROFIBRILS AS BIOMARKERS FOR DISEASE |
摘要 |
The present invention makes use of immunoassays, such as sandwich ELISAs, to profile the circulating concentration of elastic fiber and microfibril fragments in samples from individuals with diseases associated with elastic fiber and/or microfibril degradation. Examples of such diseases include, Marfan's syndrome, aortic aneurysm, and scleroderma. Profiling the concentration of such fragments can be used to diagnose disease and monitor disease progression. |
申请公布号 |
US2012174244(A1) |
申请公布日期 |
2012.07.05 |
申请号 |
US201113280644 |
申请日期 |
2011.10.25 |
申请人 |
SAKAI LYNN V.;MARSHALL LYNN M.;CARLSON ERIC J.;CHARBONNEAU NOE L.;HAYFLICK SUSAN J.;OREGON HEALTH AND SCIENCE UNIVERSITY;SHRINERS HOSPITALS FOR CHILDREN |
发明人 |
SAKAI LYNN V.;MARSHALL LYNN M.;CARLSON ERIC J.;CHARBONNEAU NOE L.;HAYFLICK SUSAN J. |
分类号 |
A01K67/027;A61K31/65;G01N33/566 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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