MODULATION OF SIDE EFFECT PROFILE OF 5-ALPHA REDUCTASE INHIBITOR THERAPY

摘要

Methods for modulating one or more side effects of 5-a-reductase inhibitor therapy are provided, where the method includes administering a 5-a-reductase inhibitor and testosterone undecanoate. Also provided are methods of maintaining or restoring a DHT serum level in an individual undergoing 5-a-reductase inhibitor therapy, where the method includes administering testosterone undecanoate in addition to 5-a-reductase inhibitor. Further provided are methods of treating or preventing a DHT -related condition, such as benign prostate hyperplasia (BPH) or prostate cancer by administering a 5-a-reductase inhibitor and testosterone undecanoate.