Disclosed is a process for preparing a treprostinil salt. The process involves the step of dissolving treprostinil in a water-miscible organic solvent to form a treprostinil solution. The treprostinil solution is reacted with an aqueous basic solution containing an alkali metal cation to form treprostinil salt. Allowing crystallization of the treprostinil salt to take place, and then collecting the treprostinil salt formed.
申请公布号
WO2012088607(A1)
申请公布日期
2012.07.05
申请号
WO2011CA50804
申请日期
2011.12.22
申请人
ALPHORA RESEARCH INC.;GIUST, WALTER;SOUZA, FABIO;OUDENES, JAN;GORIN, BORIS;BEJAN, ELENA
发明人
GIUST, WALTER;SOUZA, FABIO;OUDENES, JAN;GORIN, BORIS;BEJAN, ELENA