NEW-STABILIZED RECOMBINANT MHC PROTEIN,申请号JP20100274207-传众专利搜索

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发明名称	NEW-STABILIZED RECOMBINANT MHC PROTEIN
摘要	<P>PROBLEM TO BE SOLVED: To provide a highly stabilized MHC class II protein. <P>SOLUTION: In recombinant polypeptide served as α or β subunit of human MHC class II molecule, intermolecular interaction between at least one substituted amino acid introduced to a position outside a peptide-binding groove and peripheral amino acid is strengthened, whereby the stability of the human MHC class II molecule containing the recombinant polypeptide is improved as compared to the human MHC class II molecule constituted by the wild type α or β subunit. <P>COPYRIGHT: (C)2012,JPO&INPIT
申请公布号	JP2012120488(A)	申请公布日期	2012.06.28
申请号	JP20100274207	申请日期	2010.12.09
申请人	UNIV OF TOKYO	发明人	MIYADERA HIROKO;TOKUNAGA KATSUSHI
分类号	C12N15/09;A61K38/00;C07K14/74;G01N21/78;G01N33/53	主分类号	C12N15/09
代理机构		代理人
主权项
地址

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