PIWIL2-LIKE (PL2L) PROTEINS-TARGETED CANCER DIAGNOSIS AND THERAPY

摘要

Described herein are tumor-specific antigens called Piwil2-like (PL2L) proteins, which are useful as biomarkers for cancer diagnostics, tumor vaccines; methods to deliver multi-valent PL2L tumor vaccines; and monoclonal antibodies (mAbs) to PL2L proteins that are effective for cancer therapy.