| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a sensitive, homogeneous method for the detection of large and/or complex analytes present in biological and clinical samples. <P>SOLUTION: The present invention provides novel binding pair compositions of defined and limited stability comprising nucleic acid detection markers useful for the homogeneous, sensitive detection of analytes. Also, methods for the sensitive homogeneous detection of analytes, particularly analytes of clinical relevance are provided. The present invention provides a binding pair having a first binding member comprising a first specificity molecule coupled to a first nucleic acid, and a second binding member comprising a second specificity molecule coupled to a second nucleic acid, where the first and second nucleic acids from a duplex of defined and limited stability. <P>COPYRIGHT: (C)2012,JPO&INPIT |
