发明名称 |
RECOMBINANT BETA-GLUCOSIDASE VARIANTS FOR PRODUCTION OF SOLUBLE SUGARS FROM CELLULOSIC BIOMASS |
摘要 |
The invention relates to recombinant expression of a variant form of a fungal C1 strainβ-glucosidase. The invention also relates to the generation of fermentable sugars from biomass and the production of biofuels by fermentation of the sugars using genetically modified organisms expressing theβ-glucosidase variant. The invention provides methods for producing a fermentable sugar, such as glucose, from cellobiose by contacting cellobiose with a recombinantβ-glucosidase variant protein, such as a variant protein secreted by a recombinant host cell into culture medium. Methods of the invention may be used for conversion of a biomass substrate to a fermentable sugar, and ultimately to ethanol or other biofuel.
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申请公布号 |
US2012164709(A1) |
申请公布日期 |
2012.06.28 |
申请号 |
US201213416555 |
申请日期 |
2012.03.09 |
申请人 |
YANG JIE;ZHANG XIYUN;ANDOR ATTILA;CODEXIS, INC. |
发明人 |
YANG JIE;ZHANG XIYUN;ANDOR ATTILA |
分类号 |
C12N9/42;C12N1/15;C12N15/56;C12N15/80 |
主分类号 |
C12N9/42 |
代理机构 |
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