发明名称 |
Evolving new molecular function |
摘要 |
Nature evolves biological molecules such as proteins through iterated rounds of diversification, selection, and amplification. The power of Nature and the flexibility of organic synthesis are combined in nucleic acid-templated synthesis. The present invention provides a variety of template architectures for performing nucleic acid-templated synthesis, methods for increasing the selectivity of nucleic acid-templated reactions, methods for performing stereoselective nucleic acid-templated reactions, methods of selecting for reaction products resulting from nucleic acid-templated synthesis, and methods of identifying new chemical reactions based on nucleic acid-templated synthesis. |
申请公布号 |
US8206914(B2) |
申请公布日期 |
2012.06.26 |
申请号 |
US20100834072 |
申请日期 |
2010.07.12 |
申请人 |
LIU DAVID R.;GARTNER ZEV J.;DOYON JEFFREY B.;CALDERONE CHRISTOPHER T.;KANAN MATTHEW W.;LI XIAOYU;SNYDER THOMAS M.;ROSENBAUM DANIEL M.;PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
LIU DAVID R.;GARTNER ZEV J.;DOYON JEFFREY B.;CALDERONE CHRISTOPHER T.;KANAN MATTHEW W.;LI XIAOYU;SNYDER THOMAS M.;ROSENBAUM DANIEL M. |
分类号 |
C12N15/09;C12Q1/68;C12N15/10;C12P41/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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