PURIFICATION OF IMMUNOGENS USING A NON-POLYSACCHARIDE MATRIX

摘要

The present invention relates, at least in part, to novel and improved chromatography matrices for separating or purifying immunogens, such as, for example, viruses and viral surface proteins, from one or more contaminants in a sample, where the matrix comprises a porous non- polysaccharide solid support comprising a negatively charged, multivalent ion exchange group directly attached to the solid support.