| 发明名称 |
Crystalline compound of 7-[(3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine |
| 摘要 |
<p>A crystalline compound of 7-[(3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine (INN: Sitagliptin) of formula 1 with fumaric acid or a hydrate thereof, where the molar ratio of the compound of formula 1 to fumaric acid is 1:0.6 to 1:1.3 is described.</p> |
| 申请公布号 |
EP2464648(A1) |
申请公布日期 |
2012.06.20 |
| 申请号 |
EP20100743109 |
申请日期 |
2010.08.12 |
| 申请人 |
SANDOZ AG |
发明人 |
BLATTER, FRITZ;REICHENBAECHER, KATHARINA |
| 分类号 |
C07D487/04 |
主分类号 |
C07D487/04 |
| 代理机构 |
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