| 发明名称 |
PHARMACEUTICALLY ACTIVE SULFONYL AMINO ACID DERIVATIVE |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide sulfonyl amino acid derivatives of formula (I) notably for use as pharmaceutically active compounds, and pharmaceutical formulations containing such sulfonyl amino acid derivatives. <P>SOLUTION: The sulfonyl amino acid derivatives are efficient inhibitors of a JNK (Jun-Kinase) pathway, particularly efficient inhibitors of JNK 2 and 33. Novel sulfonyl amino acid derivatives expressed by formula (I) and methods for preparing them are further provided. <P>COPYRIGHT: (C)2012,JPO&INPIT |
| 申请公布号 |
JP2012111777(A) |
申请公布日期 |
2012.06.14 |
| 申请号 |
JP20120033338 |
申请日期 |
2012.02.17 |
| 申请人 |
MERCK SERONO SA |
发明人 |
ARKINSTALL STEPHEN;HALAZY SERGE;CHURCH DENNIS;CAMPS MONTSERRAT;RUECKLE THOMAS;GOTTELAND JEAN-PIERRE;BIAMONTE MARCO |
| 分类号 |
C07D333/34;A61K31/18;A61K31/38;A61K31/381;A61K31/44;A61K31/4436;A61K31/454;A61P1/04;A61P9/10;A61P11/06;A61P19/02;A61P25/00;A61P25/08;A61P25/14;A61P25/16;A61P25/28;A61P27/02;A61P29/00;A61P31/04;A61P35/00;A61P37/02;A61P37/06;A61P43/00;C07C311/46;C07C333/00;C07D409/12;C07D409/14 |
主分类号 |
C07D333/34 |
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