发明名称 |
SELECTIVE KINASE INHIBITORS |
摘要 |
<p>A compound of the general formula (I) or pharmaceutically acceptable prodrugs, salts, hydrates, solvates, crystal forms or diastereomers thereof, wherein A represents a variety of six membered nitrogen containing heterocyclic rings, Q is a bond, halogen, C<SUB>1-4 </SUB>alkyl, O, S, SO<SUB>2</SUB>, CO or CS and X<SUB>1</SUB>, X<SUB>2</SUB>, X<SUB>3 </SUB>and X<SUB>4 </SUB>are optionally substituted by 9 specific substituents or one can be nitrogen. Compositions comprising a carrier and at least one compound of formula (I) are also provided. Further provided are methods of treating tyrosine kinase-associated disease states by administering a compound of formula (I) and methods of suppressing the immune system of a subject by administering a compound of formula (I).</p> |
申请公布号 |
EP1704145(B1) |
申请公布日期 |
2012.06.13 |
申请号 |
EP20050700054 |
申请日期 |
2005.01.12 |
申请人 |
YM BIOSCIENCES AUSTRALIA PTY LTD |
发明人 |
STYLES, MICHELLE LEANNE;ZENG, JUN;TREUTLEIN, HERBERT, RUDOLF;WILKS, ANDREW, FREDERICK;KLING, MARCEL, ROBERT;BU, XIANYONG;BURNS, CHRISTOPHER, JOHN |
分类号 |
C07D403/04;A61K31/4439;A61K31/497;A61K31/506;A61P37/06;C07D235/30;C07D241/20;C07D401/04;C07D401/12;C07D401/14;C07D403/14;C07D405/12;C07D407/14;C07D409/14;C07D413/14 |
主分类号 |
C07D403/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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