发明名称 |
Chimeric fusion protein of Plasmodium vivax and its use |
摘要 |
PURPOSE: A gene construct encoding chimeric fusion proteins of Plasmodium vivax is provided to ensure superior reactivity and to promote immunogenicity and antigenicity. CONSTITUTION: A gene construct encoding a chimeric fusion protein of Plasmodium vivax comprises: a nucleotide sequence encoding ICB(interspecies conserved region) of merozoite surface protein-1(PvMSP-1) of Plasmodium vivax; a nucleotide sequence encoding a linker motif; and a nucleotide sequence encoding TR(tandem repeat region) of circumsporozoite protein(PvCSP) of Plasmodium vivax. The linker motif is a Gly-Pro linker. MSP-1 ICB has an amino acid of sequence number 1.
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申请公布号 |
KR20120061288(A) |
申请公布日期 |
2012.06.13 |
申请号 |
KR20100122545 |
申请日期 |
2010.12.03 |
申请人 |
UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY |
发明人 |
LEE, HO SA;LEE, SUNG JAE;CHUNG, NAM JUN;LEE, CHOONG HEE |
分类号 |
C12N15/62;A01H5/00;C07K19/00;G01N33/68 |
主分类号 |
C12N15/62 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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