发明名称 Hepatitis c virus replicons and replicon enhanced cells
摘要 The present invention features nucleic acid containing one or more adaptive mutations, and HCV replicon enhanced cells. Adaptive mutations are mutations that enhance HCV replicon activity. HCV replicon enhanced cells are cells having an increased ability to maintain an HCV replicon.
申请公布号 US8198426(B2) 申请公布日期 2012.06.12
申请号 US20030467000 申请日期 2003.07.21
申请人 PAONESSA GIACOMO;MIGLIACCIO GIOVANNI;DE FRANCESCO RAFFAELE;ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. 发明人 PAONESSA GIACOMO;MIGLIACCIO GIOVANNI;DE FRANCESCO RAFFAELE
分类号 C07H21/00;G01N33/50;C07H21/04;C07K14/18;C12N5/10;C12N7/00;C12N15/00;C12N15/09;C12N15/40;C12N15/51;C12N15/86;C12Q1/02;G01N33/15;G01N33/53;G01N33/566 主分类号 C07H21/00
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