| 发明名称 |
Method of producing tibolone metabolites by fermentation with Cunninghamella elegans |
| 摘要 |
A method of producing &Dgr;1,4-Tibolone (C21H26O2), 10&bgr;-Hydroxy-&Dgr;4-tibolone (C21H28O3). 11α,15&bgr;-Dihydroxytibolone (C21H28O4) and 11α,15&bgr;-Dihydroxy-&Dgr;5-tibolone (C21H28O4) by contacting tibolone and 3&bgr;,6&bgr;-Dihydroxytibolone (C21H32O3) by contacting 3&bgr;-hydroxytibolone with Cunninghamella elegans (ATCC 10028b) is reported. |
| 申请公布号 |
US8198041(B2) |
申请公布日期 |
2012.06.12 |
| 申请号 |
US201113015553 |
申请日期 |
2011.01.27 |
| 申请人 |
RAHMAN ATTAUR;CHOUDHARY MUHAMMED IQBAL;SHAH SYED ADNAN ALI;KHAN SHAMSUN NAHAR |
发明人 |
RAHMAN ATTAUR;CHOUDHARY MUHAMMED IQBAL;SHAH SYED ADNAN ALI;KHAN SHAMSUN NAHAR |
| 分类号 |
C12P33/00;C07J1/00;C12P33/06 |
主分类号 |
C12P33/00 |
| 代理机构 |
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