发明名称 NUCLEOSIDE DERIVATIVE AND THERAPEUTIC USE THEREOF
摘要 <P>PROBLEM TO BE SOLVED: To provide nucleoside compounds, and related synthetic methods, compositions and their therapeutic methods for the treatment of hyperproliferative disorders, including cancers, by administering nucleoside compounds. <P>SOLUTION: The present invention relates to nucleoside derivatives represented by general formulas (I) and (II), their synthetic methods and their pharmacologically acceptable salts thereof, and compositions containing such compounds, wherein Y=H or OH and X=H, F, Cl, Br, I, or CH<SB POS="POST">3</SB>. Methods for treating hyperproliferative disorders including tumors, such as breast tumors, colon tumors, lung tumors and stomach tumors, by administering the compounds are also included. <P>COPYRIGHT: (C)2012,JPO&INPIT
申请公布号 JP2012107072(A) 申请公布日期 2012.06.07
申请号 JP20120054597 申请日期 2012.03.12
申请人 REXAHN PHARMACEUTICALS INC 发明人 AHN CHANG H;CHOI WON J;LEE YOUNG B;JEONG LAK S;LEE SANG K
分类号 C07D239/47;A61K31/513;A61P35/00;A61P43/00;C07D239/46;C07D239/52;C07D239/54;C07D239/553 主分类号 C07D239/47
代理机构 代理人
主权项
地址