摘要 |
<P>PROBLEM TO BE SOLVED: To provide nucleoside compounds, and related synthetic methods, compositions and their therapeutic methods for the treatment of hyperproliferative disorders, including cancers, by administering nucleoside compounds. <P>SOLUTION: The present invention relates to nucleoside derivatives represented by general formulas (I) and (II), their synthetic methods and their pharmacologically acceptable salts thereof, and compositions containing such compounds, wherein Y=H or OH and X=H, F, Cl, Br, I, or CH<SB POS="POST">3</SB>. Methods for treating hyperproliferative disorders including tumors, such as breast tumors, colon tumors, lung tumors and stomach tumors, by administering the compounds are also included. <P>COPYRIGHT: (C)2012,JPO&INPIT |