发明名称 |
NOVEL COMPOUND AND MEDICAL USE THEREOF |
摘要 |
Provided is a levodopa prodrug that overcomes the problems attributed to the hemodynamics of levodopa, such as the development of side effects associated with a high administration frequency or frequent administration. (2S)-2-amino-3-(3,4-bis((2-(benzoyloxy)-2-methylpropanoyl)oxy)phenyl)propanoic acid or a salt or solvate thereof is a levodopa prodrug that imparts steady movement of levodopa through the blood when orally administered and is therefore useful as a preventive or therapeutic drug for the treatment of Parkinson's disease and/or Parkinsonism that overcomes the problems associated with levodopa pharmaceutical preparations. |
申请公布号 |
CA2818161(A1) |
申请公布日期 |
2012.06.07 |
申请号 |
CA20112818161 |
申请日期 |
2011.12.01 |
申请人 |
ONO PHARMACEUTICAL CO., LTD. |
发明人 |
KOKUBO, MASAYA;YANO, KOJI |
分类号 |
C07C229/36;A61K31/235;A61P25/16 |
主分类号 |
C07C229/36 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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