发明名称 NOVEL COMPOUND AND MEDICAL USE THEREOF
摘要 Provided is a levodopa prodrug that overcomes the problems attributed to the hemodynamics of levodopa, such as the development of side effects associated with a high administration frequency or frequent administration. (2S)-2-amino-3-(3,4-bis((2-(benzoyloxy)-2-methylpropanoyl)oxy)phenyl)propanoic acid or a salt or solvate thereof is a levodopa prodrug that imparts steady movement of levodopa through the blood when orally administered and is therefore useful as a preventive or therapeutic drug for the treatment of Parkinson's disease and/or Parkinsonism that overcomes the problems associated with levodopa pharmaceutical preparations.
申请公布号 CA2818161(A1) 申请公布日期 2012.06.07
申请号 CA20112818161 申请日期 2011.12.01
申请人 ONO PHARMACEUTICAL CO., LTD. 发明人 KOKUBO, MASAYA;YANO, KOJI
分类号 C07C229/36;A61K31/235;A61P25/16 主分类号 C07C229/36
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