PEPTIDE WITH SAFER SECONDARY STRUCTURE, PEPTIDE LIBRARY, AND PRODUCTION METHODS FOR SAME

摘要

The present invention addresses the problem of providing a peptide with a safer secondary structure, etc. The present invention provides a peptide that has a secondary structure made safer by a cross-linking structure. Specifically provided is a peptide that includes at least a combination of a special amino-acid indicated by formula (I) and an amino acid with a sulfanyl group in a side chain thereof [formula 1] (in the formula (A) represents a single bond or a linking group with 1-10 atoms in the main chain, (B) represents a group that includes at least on p bond, (C) represents a hydrogen atom or an alkyl group that may be substituted by a substituent, and X represents a group that can be substituted by a substitution reaction by a sulfanyl group.) The peptide has a cross-linking structure formed by a thioether bond between a side chain of the special amino acid residue and the sulfanyl group.