发明名称 |
SUBSTITUTED BENZAMIDE DERIVATIVES AS GLUCOKINASE (GK) ACTIVATORS |
摘要 |
<p>The present invention relates to substituted benzamide derivatives of the Formula I and their pharmaceutically acceptable salts, pharmaceutically acceptable solvates, enantiomers, diastereomers, prodrugs, metabolites, and polymorphs and can be useful for treating disease states mediated by glucokinase. Compounds disclosed herein can be used for reducing blood glucose levels and for increasing insulin secretion for treating type II diabetes. The invention also relates to processes for the preparation of the compounds of invention, pharmaceutical compositions containing the compounds, and their use.</p> |
申请公布号 |
EP2459554(A2) |
申请公布日期 |
2012.06.06 |
申请号 |
EP20100779053 |
申请日期 |
2010.07.22 |
申请人 |
CADILA HEALTHCARE LIMITED |
发明人 |
KHARUL, RAJENDRA;JAIN, MUKUL, R.;PATEL, PANKAJ, R. |
分类号 |
C07D413/12;A61K31/427;A61P3/10;C07D413/14;C07D417/14 |
主分类号 |
C07D413/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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