发明名称 |
System and methods for nucleic acid sequencing of single molecules by polymerase synthesis |
摘要 |
This invention relates to improved methods for sequencing and genotyping nucleic acid in a single molecule configuration. The method involves single molecule detection of fluorescent labeled PPi moieties released from NTPs as a polymerase extension product is created. |
申请公布号 |
US8192961(B2) |
申请公布日期 |
2012.06.05 |
申请号 |
US20070923599 |
申请日期 |
2007.10.24 |
申请人 |
WILLIAMS JOHN G. K.;PACIFIC BIOSCIENCES OF CALIFORNIA, INC. |
发明人 |
WILLIAMS JOHN G. K. |
分类号 |
C12N15/09;C12P19/34;C07D209/12;C07H19/10;C07H19/20;C07H21/00;C07H21/02;C07H21/04;C12M1/00;C12M1/34;C12N11/14;C12Q1/68 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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