发明名称 Synthesis method of acronycine, noracronycine or derivatives thereof
摘要 PURPOSE: A method for sythesizing acronycine, noracronycine, or derivative thereof is provided to ensure simple and efficient synthesis. CONSTITUTION: A method for preparing a compound of chemical formula 2 comprises a step of reacting 1,3-dihydroxyacridone of chemical formula 1 with NR compounds under the presence of ethylene diamine diacetate(EDDA) catalyst. The compound of chemical formula 2 is acronycine, noracronycine, or derivative thereof. A method for preparing the compound of chemical formula 2 comprises: a step of reparing 1,3-dihydroxyacridone; a step of refluxing the 1,3-dihydroxyacridone with NR compound under the presence of the catalyst; a step of adding methyl iodide; and a step of removing the solvent under pressure reduction and purifying.
申请公布号 KR20120056587(A) 申请公布日期 2012.06.04
申请号 KR20100118200 申请日期 2010.11.25
申请人 INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YEUNGNAM UNIVERSITY 发明人 LEE, YONG ROK
分类号 C07D491/052;A61K31/436;A61P35/00 主分类号 C07D491/052
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