| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide compositions useful for injection into the posterior segments of human or animal eyes. <P>SOLUTION: The compositions include small particles of a poorly soluble therapeutic agent that facilitates formation of concentrated regions of the therapeutic agent in the retinal pigmented epithelium of an eye. The particles are formed by combining a therapeutic agent with an ophthalmically acceptable polymer component. The particles have sizes less than about 3,000 nanometers, and in some cases, less than about 200 nanometers. One example of the composition includes particles of triamcinolone acetonide and hyaluronic acid whose sizes are less than about 3,000 nanometers. <P>COPYRIGHT: (C)2012,JPO&INPIT |
