WATER-FREE PHARMACEUTICAL COMPOSITIONS SUITABLE FOR LOCAL ANAESTHETICS
摘要
The present invention relates to a water-free pharmaceutical composition comprising one or more local anaesthetics in base form and which is suitable for topical administration. The composition further comprises a lipid vehicle comprising long-chain triglycerides (LCT) and at least 10 % by weight of medium-chain monoglycerides (MCM) selected so the composition has an at least semi-solid appearance at the body temperature at the site of administration. The invention further relates to methods of producing and sterilizing the compositions.
申请公布号
WO2011121034(A3)
申请公布日期
2012.05.31
申请号
WO2011EP54928
申请日期
2011.03.30
申请人
PHARMANEST AB;SUNDBERG, MARK;BRODIN, ARNE;CARLSSON, ANDERS