发明名称 |
Expandable medical device for delivery of beneficial agent |
摘要 |
An expandable medical device has a plurality of elongated struts joined together to form a substantially cylindrical device which is expandable from a cylinder having a first diameter to a cylinder having a second diameter. At least one of the plurality of struts includes at least one opening extending at least partially through a thickness of said strut. A beneficial agent is loaded into the opening within the strut in layers to achieve desired temporal release kinetics of the agent. Alternatively, the beneficial agent is loaded in a shape which is configured to achieve the desired agent delivery profile. A wide variety of delivery profiles can be achieved including zero order, pulsatile, increasing, decrease, sinusoidal, and other delivery profiles. |
申请公布号 |
US8187321(B2) |
申请公布日期 |
2012.05.29 |
申请号 |
US20050222202 |
申请日期 |
2005.09.07 |
申请人 |
SHANLEY JOHN F.;EIGLER NEAL L.;PARK KINAM;EDELMAN ELAZER R.;INNOVATIONAL HOLDINGS, LLC |
发明人 |
SHANLEY JOHN F.;EIGLER NEAL L.;PARK KINAM;EDELMAN ELAZER R. |
分类号 |
A61F2/06;A61F2/84;A61F2/00;A61F2/02;A61F2/90;A61L31/14;A61L31/16 |
主分类号 |
A61F2/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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