发明名称 PROMPT NUCLEIC ACID DELIVERY CARRIER COMPOSITION
摘要 <p>Disclosed is a nucleic acid delivery carrier which can deliver a nucleic acid (e.g., siRNA) into a cell with high efficiency when the nucleic acid is administered to an animal-derived cell or an animal body, and which is less toxic and highly safe. Also disclosed is a nucleic acid delivery composition comprising the carrier and a nucleic acid. The nucleic acid delivery carrier comprises a combination of (A) diacylphosphatidyl choline, (B) at least one member selected from the group consisting of cholesterol and a derivative thereof, and (C) an aliphatic primary amine. A nucleic acid delivery composition can be prepared by mixing the nucleic acid delivery carrier with a nucleic acid.</p>
申请公布号 NZ579804(A) 申请公布日期 2012.05.25
申请号 NZ20080579804 申请日期 2008.03.26
申请人 HIROFUMI TAKEUCHI;OTSUKA PHARMACEUTICAL CO., LTD. 发明人 TAKEUCHI, HIROFUMI;HIRA, YASUYUKI;NAKANO, KOJI;TOYOBUKU, HIDEKAZU
分类号 A61K47/28;A61K9/127;A61K31/7088;A61K31/713;A61K47/18;A61K47/24;A61K48/00 主分类号 A61K47/28
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