发明名称 PROCESS FOR CONCENTRATION OF ANTIBODY AND THERAPEUTIC PRODUCT THEREOF
摘要 <P>PROBLEM TO BE SOLVED: To provide highly concentrated antibody compositions, and to provide a process for preparing highly concentrated antibody products. <P>SOLUTION: A process for preparing the highly concentrated antibody compositions includes: a step of subjecting a first antibody preparation to a first ultrafiltering, thereby providing a second antibody preparation; and a step of diafiltering the second antibody preparation; and then subjecting the second antibody preparation to second ultrafiltering, wherein one or more of the steps are accomplished at about 30&deg;C to about 50&deg;C. <P>COPYRIGHT: (C)2012,JPO&INPIT
申请公布号 JP2012097086(A) 申请公布日期 2012.05.24
申请号 JP20110256451 申请日期 2011.11.24
申请人 GENENTECH INC;NOVARTIS AG 发明人 WINTER CHARLES MATTHEW
分类号 C07K1/34 主分类号 C07K1/34
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