The present invention relates to the use of quinolinone derivatives of general formula (I), ligands of the Smo receptor or of related receptors which target a binding site of the receptor which is different from the known ligand binding sites, as research tools for identifying modulators of the Smo receptor or of related receptors, characterizing the Hedgehog signalling pathway and diagnosis; the invention also relates to kits containing said derivatives of general formula (I).
申请公布号
WO2012066479(A1)
申请公布日期
2012.05.24
申请号
WO2011IB55098
申请日期
2011.11.15
申请人
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;RUAT, MARTIAL;FAURE, HELENE;GOROJANKINA, TATIANA