METHODS FOR TREATING EARLY STAGE OR MILD NEUROLOGICAL DISORDERS

摘要

This disclosure relates to modulation of the interactions between proNTs and p75NTR/SorCS2 expressed on neuronal cells. Inhibition of such interactions is useful for reducing unwanted synaptic elimination, neurite pruning and/or other neuronal structural collapses, and for treating early stage and mild neurological disorders including mild cognitive impairment.