发明名称 STEALTH POLYMERIC PARTICLES FOR DELIVERY OF BIOACTIVE OR DIAGNOSTIC AGENTS
摘要 The present invention is directed to a crosslinked or non-crosslinked polymer particle, wherein the crosslinked polymer particle comprises a copolymer of poly(alklyene glycol-graft-acrylate) that is crosslinked by at least one hydrolysable monomer or crosslinking agent. The present invention is also directed to a polymer particle comprising a crosslinked polymer particle that is a product of starting materials comprising (a) a hydrophilic monomer, (b) a hydrophobic monomer, and (c) a hydrolysable crosslinking agent (the crosslinking agent may be absent in the case of non-crosslinked particles). The present invention is still further directed to a polymer particle comprising a crosslinked copolymer, where the crosslinked copolymer includes structures represented by Formulas (I), (II), and (III), as defined in the specification. Other embodiments of the present invention also include methods of manufacturing polymer particles.
申请公布号 US2012129798(A1) 申请公布日期 2012.05.24
申请号 US20100952856 申请日期 2010.11.23
申请人 AKALA EMMANUEL;OKUNOLA OLUYOMI 发明人 AKALA EMMANUEL;OKUNOLA OLUYOMI
分类号 A61K31/337;A61K31/135;A61K31/704;C08F8/00;C08F8/32;C08F265/06 主分类号 A61K31/337
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