发明名称 |
COMPOUND HAVING STRUCTURE DERIVED FROM MONONUCLEOSIDE OR MONONUCLEOTIDE, NUCLEIC ACID, LABELING SUBSTANCE, AND METHOD AND KIT FOR DETECTION OF NUCLEIC ACID |
摘要 |
<p>Disclosed is a labeling substance which enables to detect a double-stranded structure in a nucleic acid effectively. Specifically disclosed is: a compound having a structure derived from a mononucleoside or mononucleotide, wherein the structure is represented by the formula (1), (1b) or (1c); a tautomer or stereoisomer of the compound; or a salt of the compound, the tautomer or the stereoisomer. (1) (1b) (1c) wherein B represents an atomic group having a nucleobase skeleton; E represents an atomic group having a deoxyribose skeleton, a ribose skeleton or a structure derived from the deoxyribose skeleton or the ribose skeleton, or an atomic group having a peptide structure or a peptoid structure; and Z 11 and Z 12 independently represent a hydrogen atom, a protecting group or a fluorescent atomic group, and may be the same as or different from each other.</p> |
申请公布号 |
EP2130835(B1) |
申请公布日期 |
2012.05.23 |
申请号 |
EP20080721474 |
申请日期 |
2008.03.06 |
申请人 |
RIKEN |
发明人 |
OKAMOTO,AKIMITSU;IKEDA, SHUJI;KUBOTA, TAKESHI |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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