发明名称 |
DNA FRAGMENT AND PHARMACEUTICAL COMPOSITION |
摘要 |
Provided are a DNA fragment, a pharmaceutical composition, and the like, which can simplify the period of creating knockout animals. The DNA fragment includes: a detection sequence that codes for a detection marker other than drug resistance (preferably a visually-detectable marker); a resistance sequence that codes for a resistance marker for a drug that inhibits the proliferation of one or more species of at least prokaryotic organisms; a promoter sequence that is located upstream of the resistance sequence and functions in prokaryotic organisms; and a regulatory sequence that is located upstream of all of the above sequences and, only when inserted into a target region of the genome of at least one species of eukaryotic organism, induces the expression of a sequence located downstream. The detection sequence and the resistance sequence are arranged so as to be capable of action.
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申请公布号 |
US2012124681(A1) |
申请公布日期 |
2012.05.17 |
申请号 |
US201013383648 |
申请日期 |
2010.07.16 |
申请人 |
SHINDO TAKAYUKI;SAKURAI TAKAYUKI;IMMUNO-BIOLOGICAL LABORATORIES CO., LTD. |
发明人 |
SHINDO TAKAYUKI;SAKURAI TAKAYUKI |
分类号 |
A61K49/00;A61K31/711;C12N5/10;C12N15/11;C12N15/85;C12Q1/02;C12Q1/68 |
主分类号 |
A61K49/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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