发明名称 QUATERNISED AMMONIUM CYCLODEXTRIN COMPOUNDS FOR USE AS ANTIMICROBIAL AGENTS, PRESERVATIVES AND PENETRATION ENHANCERS
摘要 Use of a compound of formula (I), wherein the symbol (a) represents a n-valent residue derived from a cyclodextrin compound by removing n of its hydroxyl groups; n is a number greater than 0 and represents the average number of substituents of formula (II) per molecule of said compound; h is 0 or 1; R1 is a di-valent group selected from alkylene, hydroxy alkylene, halogeno alkylene, monocyclic aralkylene, cycloalkylene and phenylene; R2, R3 and R4 are each independently of one another a group selected from alkyl, cycloalkyl, aryl, aralkyl and cycloheteryl; Xm- is a m-fold negatively charged anion; m is an integer being equal or greater than 1; and k is n/m in the preparation of an anti-infective medicament, as preservative and penetration enhancer.
申请公布号 CA2487332(C) 申请公布日期 2012.05.15
申请号 CA20032487332 申请日期 2003.06.12
申请人 NOVARTIS AG 发明人 KIS, GEORG LUDWIG;SCHOCH, CHRISTIAN;SZEJTLI, JOZSEF
分类号 A61K31/724;A61K47/30;A61K45/00;A61K47/32;A61K47/34;A61K47/36;A61K47/38;A61K47/40;A61P17/00;A61P27/02;A61P31/00;A61P31/04;C08B37/16 主分类号 A61K31/724
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