发明名称 |
THERAPEUTIC COMBINATION COMPRISING A PLK1 INHIBITOR AND AN ANTINEOPLASTIC AGENT |
摘要 |
The present invention provides a combination comprising (a) a compound of formula (I) and (b) one or more antineoplastic agents selected from the group consisting of an antimetabolite agent, analkylating or alkylating-like agent, an intercalating agent, a topoisomerase I or II inhibitor, an antimitotic agent, a kinase inhibitor, a proteasome inhibitor and an antibody inhibiting a growth factor or its receptor, wherein active ingredients of the combination are present in each case in free form or in the form of a pharmaceutically acceptable salt or any hydrate or solvate thereof, useful in the treatment of tumors.
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申请公布号 |
US2012114641(A1) |
申请公布日期 |
2012.05.10 |
申请号 |
US201013321024 |
申请日期 |
2010.05.21 |
申请人 |
VALSASINA BARBARA;BERIA ITALO;CIAVOLELLA ANTONELLA;BALLINARI DARIO;PESENTI ENRICO;CROCI VALTER DOMENICO;CASNAGHI MARA EMANUELA;CROCI ALESSANDRO LUCIANO;MOLL JUERGEN;NERVIANO MEDICAL SCIENCES S.R.L. |
发明人 |
VALSASINA BARBARA;BERIA ITALO;CIAVOLELLA ANTONELLA;BALLINARI DARIO;PESENTI ENRICO;CROCI VALTER DOMENICO;CASNAGHI MARA EMANUELA;CROCI ALESSANDRO LUCIANO;MOLL JUERGEN |
分类号 |
A61K31/519;A61K31/337;A61K31/704;A61K31/7068;A61K33/24;A61K38/14;A61K39/395;A61P35/00 |
主分类号 |
A61K31/519 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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