发明名称 |
STORAGE-STABLE, ANTI-MICROBIAL COMPOSITIONS INCLUDING CERAGENIN COMPOUNDS AND METHODS OF USE |
摘要 |
Storage- stable, anti-microbial compositions and products include a carrier and a ceragenin compound suspended in the carrier. Ceragenin compounds suspended in the carrier include a sterol backbone and a number of cationic groups attached to the sterol backbone via hydrolysable linkages. The carrier has a pH of 5.5 or less, which acts to stabilize the hydrolysable linkages and increase the shelf-life of the anti-microbial compositions and anti-microbial products. Nevertheless, the ceragenin compounds described herein are designed to break down relatively quickly (e.g., within about 5 days) if the pH environment of the ceragenin compounds is raised to about pH 6.5 or greater. |
申请公布号 |
WO2012061648(A1) |
申请公布日期 |
2012.05.10 |
申请号 |
WO2011US59225 |
申请日期 |
2011.11.03 |
申请人 |
BRIGHAM YOUNG UNIVERSITY;SAVAGE, PAUL, B. |
发明人 |
SAVAGE, PAUL, B. |
分类号 |
A01N25/04;A01N45/00;A01P1/00 |
主分类号 |
A01N25/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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